General Characteristics
Age: | 56 years |
Gender: | Female |
Disease Origin: | Sacral |
Disease Status: | Recurrent, Metastatic |
Metastatic Site(s): | Liver, Peritoneum |
Sample Origin: | Peritoneum |
Prior Radiation: | Yes |
Prior Systemic Therapy: | No |
Source: | Francis Hornicek, Zhenfeng Duan Massachusetts General Hospital |
Molecular Features
Cell Morphology: | Physaliferous |
TBXT Expression: | Positive; 20x that of U-CH2 |
TBXT Localization: | Nuclear |
CD24 Expression: | Positive; 18x that of U-CH2 |
HLA Type: | |
Sequence Data: | WGS and transcriptome data available: raw sequencing data in Cavatica (Chordoma Foundation Dataset) and summary data in PedcBioportal. Contact researchteam@chordoma.org with any questions. |
SMARCB1 Status: | No expression |
Validation Results: | Validation Report |
Growth Conditions
Growth Medium: | RPMI +10% FBS |
Freeze Medium: | 70% complete growth medium supplemented with an additional 20% fetal bovine serum and 10% DMSO |
Culture Conditions: | Temperature: 37°C Atmosphere: air, 95%; carbon dioxide (CO2), 5% |
Subculturing Instructions: | Cell Culture Procedures |
Publications
Characterized By:
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