General Characteristics
| Age: | <20 years |
| Gender: | Female |
| Disease Origin: | Clival |
| Disease Status: | Recurrent, Metastatic |
| Metastatic Site(s): | Pineal, Brain dura, Lower spinal cord |
| Sample Origin: | Pineal gland |
| Prior Radiation: | N/A |
| Prior Systemic Therapy: | N/A |
| Source: | Kevin Mellert, Peter Moller University of Ulm |
| Notes: | This cell line was derived from the CF359B PDX model |
Molecular Features
| Cell Morphology: | Physaliferous |
| TBXT Expression: | Positive; 1x that of U-CH1 |
| TBXT Localization: | Nuclear |
| CD24 Expression: | |
| HLA Type: | |
| Sequence Data: | WES and transcriptome data available: raw sequencing data in Cavatica (Chordoma Foundation Dataset) and summary data in PedcBioportal. Contact researchteam@chordoma.org with any questions. |
| SMARCB1 Status: | No expression |
| Validation Results: | Validation Report |
Growth Conditions
| Growth Medium: | IMDM : RPMI-1640 (4:1) + 10% FCS, L-glutamnine |
| Freeze Medium: | 70% complete growth medium supplemented with an additional 20% fetal bovine serum and 10% DMSO |
| Culture Conditions: | Temperature: 37°C Atmosphere: air, 95%; carbon dioxide (CO2), 5% |
| Subculturing Instructions: | Cell Culture Procedures |
Publications
Characterized By:
|